| Notre Dame Games/Schedule |
| Regular Season |
| Nov. 15, 2015 | Day 3 | Notre Dame (2) - Bucknell | 85-54  |
| Nov. 18, 2015 | Day 6 | Notre Dame (2) - Toledo | 74-39 |
| Nov. 21, 2015 | Day 9 | S.Dakota St. - Notre Dame (2) | 64-75 |
| Nov. 23, 2015 | Day 11 | Valparaiso - Notre Dame (2) | 54-110 |
| Nov. 27, 2015 | Day 15 | Notre Dame (2) - Denver | 94-52 |
| Nov. 28, 2015 | Day 16 | Notre Dame (2) - UCLA (10) | 92-84 |
| Dec. 2, 2015 | Day 20 | Notre Dame (2) - Ohio St. (9) | 75-72 |
| Dec. 5, 2015 | Day 23 | Connecticut (1) - Notre Dame (2) | 91-81  |
| Dec. 9, 2015 | Day 27 | Notre Dame (2) - De Paul (18) | 95-90 |
| Dec. 12, 2015 | Day 30 | TCU - Notre Dame (2) | 72-88 |
| Dec. 20, 2015 | Day 38 | Longwood - Notre Dame (2) | 83-32 |
| Dec. 21, 2015 | Day 39 | St.Joseph's - Notre Dame (2) | 55-91 |
| Dec. 28, 2015 | Day 43 | Notre Dame (2) - Oregon St. (6) | 62-61 |
| Dec. 30, 2015 | Day 45 | Notre Dame (2) - Georgia Tech | 85-76 |
| Jan. 3, 2016 | Day 49 | Pittsburgh - Notre Dame (2) | 55-65 |
| Jan. 7, 2016 | Day 53 | Virginia - Notre Dame (2) | 46-74 |
| Jan. 10, 2016 | Day 56 | notre dame (2) - N.Carolina | 88-54 |
| Jan. 14, 2016 | Day 60 | Boston Coll. - Notre Dame (2) | 50-63 |
| Jan. 18, 2016 | Day 64 | Notre Dame (2) - Tennessee | 79-66 |
| Jan. 21, 2016 | Day 67 | Notre Dame (2) - Syracuse (14) | 90-62 |
| Jan. 24, 2016 | Day 70 | Notre Dame (2) - Virginia Tech | 80-41 |
| Jan. 28, 2016 | Day 74 | Georgia Tech - Notre Dame (2) | 42-54 |
| Feb. 1, 2016 | Day 78 | Duke - Notre Dame (2) | 61-68 |
| Feb. 4, 2016 | Day 81 | N.Carolina St. - Notre Dame (2) | History |
| Feb. 7, 2016 | Day 84 | Louisville (8) - Notre Dame (2) | 61-66 |
| Feb. 14, 2016 | Day 91 | Notre Dame (2) - Miami, FL (20) | 90-69 |
| Feb. 18, 2016 | Day 95 | Notre Dame (2) - Wake Forest | 86-52 |
| Feb. 22, 2016 | Day 99 | Notre Dame (2) - Florida St. (17) | 73-66 |
| Feb. 25, 2016 | Day 102 | Clemson - Notre Dame (2) | 52-71 |
| Feb. 27, 2016 | Day 104 | Boston Coll. - Notre Dame (2) | 58-70 |
| Mar. 4, 2016 | Day 110 | Duke - Notre Dame (2) | 54-83 |
| Mar. 5, 2016 | Day 111 | Miami, FL (20) - Notre Dame (2) | 67-78 |
| Mar. 6, 2016 | Day 112 | Syracuse (14) - Notre Dame (2) | 57-68 |
| National Tournament Day 1 |
| Mar. 19, 2016 | Day 123 | N.Carolina A&T - Notre Dame (2) | 61-95 |
| National Tournament Day 2 |
| Mar. 21, 2016 | Day 125 | Indiana - Notre Dame (2) | 70-87 |
| Regional Semifinals |
| Mar. 25, 2016 | Day 127 | Stanford (13) - Notre Dame (2) | 90-84 |
